BETAZOLE HYDROCHLORIDE
- Product Name
- BETAZOLE HYDROCHLORIDE
- CAS No.
- 138-92-1
- Chemical Name
- BETAZOLE HYDROCHLORIDE
- Synonyms
- histalog;Histimin;gastramine;Histalog (TN);betazolehydrochloride;betazoledihydrochloride;2-(3-Pyrazolyl)ethylamin;ametazoledihydrochloride;Betazole hydrochloride (JAN);BETAZOLE HYDROCHLORIDE (200 MG)
- CBNumber
- CB0501633
- Molecular Formula
- C5H11Cl2N3
- Formula Weight
- 184.06694
- MOL File
- 138-92-1.mol
BETAZOLE HYDROCHLORIDE Property
- Melting point:
- 224-226°
- storage temp.
- Store at -20°C
- solubility
- DMSO: 37 mg/mL (201.01 mM);Ethanol: 18 mg/mL (97.79 mM)
- Water Solubility
- Water: 37 mg/mL (201.01 mM)
Safety
- HS Code
- 2933199090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B276680
- Product name
- BetazoleDihydrochloride
- Packaging
- 2.5mg
- Price
- $160
- Updated
- 2021/12/16
- Product number
- FP126823
- Product name
- Betazole dihydrochloride
- Packaging
- 250mg
- Price
- $172.5
- Updated
- 2021/12/16
- Product number
- FP126823
- Product name
- Betazole dihydrochloride
- Packaging
- 2g
- Price
- $867
- Updated
- 2021/12/16
- Product number
- OR471576
- Product name
- 2-(3-Pyrazolyl)ethanaminedihydrochloride
- Packaging
- 5g
- Price
- $1827
- Updated
- 2021/12/16
- Product number
- 077451
- Product name
- [2-(1H-Pyrazol-3-yl)ethyl]amine dihydrochloride
- Packaging
- 5g
- Price
- $2310
- Updated
- 2021/12/16
BETAZOLE HYDROCHLORIDE Chemical Properties,Usage,Production
Originator
Histalog,Lilly,US,1953
Uses
Betazole Hydrochloride is a histamine H2 receptor agonist that is used as a gastric stimulant for the investigation of gastric secretion activity.
Definition
ChEBI: The dihydrochloride salt of betazole.
Manufacturing Process
A solution of 55 grams (1.1 mol) of hydrazine hydrate in 100 ml of methanol was cooled in a water bath and stirred while a solution of 48 grams (0.50 mol) of pure γ-pyrone in 100 ml of methanol was added over a period of about 15 minutes. After the addition was complete, the solution was allowed to stand at room temperature for about 1 hour, and was placed in a 1 liter hydrogenation bomb. 25 ml of liquid ammonia were added cautiously with stirring, followed by about 15 cc of Raney nickel catalyst. The bomb was charged with hydrogen to 1,800 pounds pressure, heated to 90°C and agitated. The quantity of hydrogen required to convert the hydrazone into the desired aminoethylpyrazole was taken up in about 3 hours. The bomb was cooled and opened, and the contents filtered. The filtrate was evaporated under reduced pressure to remove the methanol and the residual liquid was distilled under reduced pressure, whereby there were obtained 44.5 grams (81% yield) of 3-β-aminoethylpyrazole boiling at 118°-123°C at a pressure of 0.5 mm of Hg.
brand name
Histalog (Lilly).
Therapeutic Function
Diagnostic aid (gastric secretion)
BETAZOLE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
BETAZOLE HYDROCHLORIDE Suppliers
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